Potions

Data Version: v0.102.0 (2026-04-02)

Browse all 63 potions in Slay the Spire 2

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Attack Potion

Attack Potion

Common
Choose 1 of 3 random Attack cards to add into your Hand. It's free to play this turn.
Block Potion

Block Potion

Common
Gain 12 Block.
Blood Potion

Blood Potion

Common
Heal for 20% of your Max HP.
Colorless Potion

Colorless Potion

Common
Choose 1 of 3 random Colorless cards to add into your Hand. It's free to play this turn.
Dexterity Potion

Dexterity Potion

Common
Gain 2 Dexterity.
Energy Potion

Energy Potion

Common
Gain 2.
Explosive Ampoule

Explosive Ampoule

Common
Deal 10 damage to ALL enemies.
Fire Potion

Fire Potion

Common
Deal 20 damage.
Flex Potion

Flex Potion

Common
Gain 5 Strength. At the end of your turn, lose 5 Strength.
Focus Potion

Focus Potion

Common
Gain 2 Focus.
Poison Potion

Poison Potion

Common
Apply 6 Poison.
Potion of Doom

Potion of Doom

Common
Apply 33 Doom.
Power Potion

Power Potion

Common
Choose 1 of 3 random Power cards to add into your Hand. It's free to play this turn.
Skill Potion

Skill Potion

Common
Choose 1 of 3 random Skill cards to add into your Hand. It's free to play this turn.
Speed Potion

Speed Potion

Common
Gain 5 Dexterity. At the end of your turn, lose 5 Dexterity.
Star Potion

Star Potion

Common
Gain 3.
Strength Potion

Strength Potion

Common
Gain 2 Strength.
Swift Potion

Swift Potion

Common
Draw 3 cards.
Vulnerable Potion

Vulnerable Potion

Common
Apply 3 Vulnerable.
Weak Potion

Weak Potion

Common
Apply 3 Weak.
Ashwater

Ashwater

Uncommon
Exhaust any number of cards in your Hand.
Blessing of the Forge

Blessing of the Forge

Uncommon
Upgrade all cards in your Hand for the rest of combat.
Bone Brew

Bone Brew

Uncommon
Summon 15.
Clarity Extract

Clarity Extract

Uncommon
Draw 1 card. At the start of your next turns, draw 1 additional card.
Cunning Potion

Cunning Potion

Uncommon
Add 3 Upgraded Shivs into your Hand.
Cure All

Cure All

Uncommon
Gain 1. Draw 2 cards.
Duplicator

Duplicator

Uncommon
This turn, your next card is played an extra time.
Fortifier

Fortifier

Uncommon
Triple your Block.
Fysh Oil

Fysh Oil

Uncommon
Gain 1 Strength and 1 Dexterity.
Gambler's Brew

Gambler's Brew

Uncommon
Discard any number of cards, then draw that many.
Heart of Iron

Heart of Iron

Uncommon
Gain 7 Plating.
King's Courage

King's Courage

Uncommon
Forge 15.
Liquid Bronze

Liquid Bronze

Uncommon
Gain 3 Thorns.
Potion of Binding

Potion of Binding

Uncommon
Apply 1 Weak and 1 Vulnerable to ALL enemies.
Potion of Capacity

Potion of Capacity

Uncommon
Gain 2 Orb Slots.
Powdered Demise

Powdered Demise

Uncommon
Enemy loses 9 HP at the end of each of its turns.
Radiant Tincture

Radiant Tincture

Uncommon
Gain 1. Gain an additional at the start of your next 3 turns.
Regen Potion

Regen Potion

Uncommon
Gain 5 Regen.
Stable Serum

Stable Serum

Uncommon
Retain your Hand for 2 turns.
Touch of Insanity

Touch of Insanity

Uncommon
Choose a card in your Hand. It is free to play this combat.
Beetle Juice

Beetle Juice

Rare
Enemy's attacks deal 30% less damage for the next turns.
Bottled Potential

Bottled Potential

Rare
Shuffle ALL your cards into your Draw Pile. Draw 5 cards.
Cosmic Concoction

Cosmic Concoction

Rare
Add 3 Upgraded Colorless cards into your Hand.
Distilled Chaos

Distilled Chaos

Rare
Play the top 3 cards of your Draw Pile.
Droplet of Precognition

Droplet of Precognition

Rare
Choose a card in your Draw Pile and add it into your Hand.
Entropic Brew

Entropic Brew

Rare
Fill all your empty potion slots with random potions.
Essence of Darkness

Essence of Darkness

Rare
Channel a Dark for each of your Orb Slots.
FairyInABottle

FairyInABottle

Rare
Fruit Juice

Fruit Juice

Rare
Gain 5 Max HP.
GhostInAJar

GhostInAJar

Rare
Gigantification Potion

Gigantification Potion

Rare
The next Attack you play deals triple damage.
Liquid Memories

Liquid Memories

Rare
Put a card from your Discard Pile into your Hand. It costs 0 this turn.
Lucky Tonic

Lucky Tonic

Rare
Gain 1 Buffer.
Mazaleth's Gift

Mazaleth's Gift

Rare
Gain 1 Ritual.
Orobic Acid

Orobic Acid

Rare
Add a random Attack, Skill, and Power into your Hand. They're free to play this turn.
Pot of Ghouls

Pot of Ghouls

Rare
Add 2 Souls into your Hand.
Shackling Potion

Shackling Potion

Rare
ALL enemies lose 7 Strength this turn.
ShipInABottle

ShipInABottle

Rare
Snecko Oil

Snecko Oil

Rare
Draw 7 cards. Randomize the cost of cards in your Hand this turn.
Soldier's Stew

Soldier's Stew

Rare
All cards containing Strike gain 1 Replay this combat.